We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More
Most Useful Reviews
9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
Read More
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
Read More
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More
User Reviews
USERS' SCORE
Good
Based on 139 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
Read More
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
Read More
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
Read More
9
Cartilage restoration
64 people found this helpful
A good product! I have long suffered from a sore neck and back due to my sedentary office work and lifestyle. Initially, I didn't seek medical advice, but eventually, I had an MRI that revealed arthritis. The doctor assured me that gymnastics and chondroprotectors could help ease the pain and improve my quality of life. After about a year of exercise, I found some relief but was still in discomfort. I ordered from iHerb, knowing it offers a good selection at reasonable prices. Chondroprotectors help restore cartilage tissue, although the benefits take time, becoming apparent after several weeks. My doctor indicated I may need to take them long-term as they don't affect the stomach or liver. They provide me with relief after about two weeks, and I highly recommend them!
Read More
9
Knee pain relief
11 people found this helpful
Super remedy! I use it for my husband's koksartroz, and the pain in his knee has ceased. We consistently order this product.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Glucosamine Chondroitin formulas are dietary supplements commonly used to support joint health and alleviate symptoms associated with osteoarthritis. These formulas typically contain glucosamine, a naturally occurring compound in the body that contributes to the formation and repair of cartilage, and chondroitin sulfate, which helps cartilage retain water and maintain its elasticity. Together, these ingredients are believed to promote joint function, reduce pain, and improve overall mobility, particularly in individuals who experience wear and tear on their joints due to age, physical activity, or injury.
The efficacy of glucosamine and chondroitin supplements can vary from person to person, and while some users report significant relief from joint discomfort, scientific studies on their effectiveness have produced mixed results. It's essential to consult with a healthcare provider before adding these supplements to your routine, especially if you have existing health conditions or are taking other medications. Many brands also blend these ingredients with additional vitamins, minerals, or herbal extracts to enhance their joint-supporting benefits, making it crucial to read labels and choose formulas that fit your specific needs.
Based on user reviews, the timeline for experiencing results from this supplement can vary, but many users report relief within a relatively short period. For example, several reviewers noted significant improvements after just two weeks of use, where issues such as joint pain and discomfort subsided (Read Review; Read Review; Read Review). Some users even experienced noticeable changes within a week (Read Review; Read Review).
However, others have indicated that substantial benefits might become more apparent after a longer duration—around three months or more (Read Review; Read Review). For chronic conditions, users suggest that a longer commitment to the supplement may be necessary to achieve optimal effects, with recommendations to use it for at least three months (Read Review). As with any supplement, individual results can vary, so consistency in taking the product is key for those with autoimmune disorders.
This specific supplement does not have sufficient scientific backing to support its use for Autoimmune Disorders based on current research. One study identified the association of KCNA2 IgG autoantibodies with neuropsychiatric disorders and suggested that immunotherapy may benefit some patients, especially those with autoimmune encephalitis [1]. However, this indicates preliminary findings that emphasize the necessity for further studies to clarify the role of KCNA2 autoimmunity and potential therapeutic avenues.
Based on user reviews, many individuals have reported substantial improvements in their joint-related symptoms after using this supplement. For instance, one user mentioned a complete halt to their knee pain and a significant reduction in discomfort within just one week of starting the product (Read Review; Read Review). Others, particularly those with chronic conditions like psoriatic arthritis or degenerative disc disease, claimed notable relief after a few weeks of consistent usage, allowing them to enjoy daily activities without pain (Read Review; Read Review).
Additionally, several users noted that long-term use, often suggested to span three months or more, can lead to even greater benefits. For example, one user with long-standing joint pain experienced significant relief after sustained use over half a year, finding that the discomfort ceased altogether for a full year post-treatment (Read Review). Another user also confirmed that while initial relief was felt within about two weeks, a longer duration of use proved essential for optimal improvement (Read Review). As highlighted in these anecdotes, individual results may vary, but the overall trend shows a positive response to the supplement.
Based on user reviews, many individuals with autoimmune disorders have reported positive experiences when combining this supplement with their existing regimen for managing their conditions. Users highlighted its effectiveness in relieving joint-related issues, with one reviewer specifically noting that the combination of glucosamine, chondroitin, and MSM significantly improved their condition without the side effects often associated with synthetic medications (Read Review). Furthermore, some users indicated that taking this supplement alongside their health routines, such as exercise or other treatments, enhanced their overall results. For instance, one user shared that they experienced substantial pain relief after integrating this supplement with long-term chondroprotectors and physical therapy, suggesting a synergistic effect (Read Review).
Additionally, consistent use of the supplement has been praised, as many users mentioned that it took time—often several weeks or months—for them to see significant changes (Read Review; Read Review). Several reviewers noted the importance of maintaining a long-term regimen to manage their autoimmune symptoms effectively. This aligns with the feedback from a user who highlighted the noticeable improvements in joint comfort and mobility over months of consistent use (Read Review). Overall, users seem to find that combining this supplement with their current treatments enhances their quality of life significantly.
Users report varied experiences regarding the optimal dosage of Glucosamine Chondroitin formulas for treating autoimmune disorders. Many found that significant relief occurred after consistent use over a period of weeks or months. For instance, one user mentioned that after two weeks with the proper dosage, their joint discomfort noticeably diminished (Read Review). Another noted that, while a noticeable effect took a month, they experienced remarkable improvement thereafter (Read Review). A user indicated a preference for a longer treatment duration, recommending a three-month commitment to benefit fully from the product (Read Review).
Additionally, the general consensus suggests that it’s beneficial to adhere to recommended dosages, as one user observed substantial improvements in their condition after sticking to their dosage twice a year (Read Review). Importantly, users emphasized that the product's effects can become more pronounced with continued use, suggesting that patience and consistency are key in managing symptoms associated with autoimmune disorders (Read Review). While individual responses may vary, most users agreed that a sustained approach tends to yield the best outcomes.
9
Stops joint pain
11 people found this helpful
My husband benefited from this product. After two weeks of taking the capsules, his joints stopped hurting, benefiting from my recommendation. I have now started my mother on it. This package offers excellent value for price and quantity. The combination of Chondroitin, Glucosamine, and MSM is recommended for at least three months. I appreciate IHERB's fast delivery; the order arrived within just five days.
7.5
Joint pain relief
8 people found this helpful
I ordered this supplement for my mother, as she was experiencing hip joint pain. After about two weeks of use, she reported that her joints stopped crunching and the pain significantly reduced. I will be ordering more since the treatment requires two bottles. The capsules are easy to swallow, and I have faith in the Doctor's Best brand for dietary supplements.
9
Rapid results
7 people found this helpful
I purchased this for my husband due to ongoing knee problems. I switched from Japanese products to this glucosamine and chondroitin. Incredibly, the results were apparent within a week; his knee swelling and pain vanished. His job as a mechanic demands he is on his feet constantly, and he now feels much better. I highly recommend it!
9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
9
Pain relief achieved
6 people found this helpful
My relationship with the iHerb website began with this chondroprotector, which is effective for joint problems. After taking it for two weeks, my long-standing back and knee pain disappeared, despite carrying my large baby. I'm delighted with the results and will definitely recommend it.
9
Pain relief success
7 people found this helpful
I’m now on my second order of this remarkable remedy for joint pain. I bought it for my husband, who had chronic joint pain lasting over a year, and after just one course, his pain greatly diminished. I also suffer from chronic osteochondrosis, and after taking it for three months, I noticed significant improvement with no discomfort. My mother, at 70, is eager to try it for her shoulder and back pain. I've concluded it's wise to take this twice a year.
10
Knee pain gone
4 people found this helpful
I am 78 years old and started experiencing severe pain in my left knee nine months ago, which confined me to using Voltaren tablets. As I can't take pain medication for extended periods, I switched to Glucosamine Sulfate with Chondroitin tablets. After four months, I saw slight pain reduction but no further improvement. I then tried Glucosamine+Chondroitin with MSM and noticed a significant change after three months; my knee pain completely vanished. I can now walk without fear of sudden sharp pain! I continue taking these pills to maintain my knee health. I am immensely grateful for this help.
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
9
Sustained effect
5 people found this helpful
My mother endured degenerative disc disease for years, but after two months on this complex, she no longer experiences pain. I’m thrilled with the cost-effectiveness and quality of the product.
9
Effective for pain
8 people found this helpful
It is the best supplement for joints I have ever used! I experienced knee pain since I was 25. After using it according to the guidelines for half a year, I felt no discomfort for a year following treatment. I will continue to order it repeatedly because it truly works.
9
Cartilage restoration
64 people found this helpful
A good product! I have long suffered from a sore neck and back due to my sedentary office work and lifestyle. Initially, I didn't seek medical advice, but eventually, I had an MRI that revealed arthritis. The doctor assured me that gymnastics and chondroprotectors could help ease the pain and improve my quality of life. After about a year of exercise, I found some relief but was still in discomfort. I ordered from iHerb, knowing it offers a good selection at reasonable prices. Chondroprotectors help restore cartilage tissue, although the benefits take time, becoming apparent after several weeks. My doctor indicated I may need to take them long-term as they don't affect the stomach or liver. They provide me with relief after about two weeks, and I highly recommend them!
7.5
Reduced stiffness
5 people found this helpful
At 47, I began experiencing stiffness in my finger joints. By 48, my elbow joints also felt tight upon waking. I started taking glucosamine chondroitin with MSM last April and have noticed significant improvement. I no longer wake with stiffness or knee pain. I plan to continue as I've found the benefits greatly help with my autoimmune disorder symptoms.
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
9
Remarkable recovery
5 people found this helpful
I was sceptical that this would help with my serious issues of spondylarthrosis and arthrosis. After failing with prescribed treatments, I stumbled upon this supplement and, out of desperation, decided to try it. Remarkably, after just a month, I noticed a substantial decrease in pain and improvement in my general health, even enjoying a wine without hangover. I plan to order for my father as well.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.
Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.